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Plinest + NCTF Combination Treatment — Pioneering Regenerative Aesthetics at Clique Clinic

Key Takeaways

  • Pli-NCTF is the world’s first regenerative aesthetic cocktail, combining Plinest and NCTF 135HA for deep skin rejuvenation at the cellular level.
  • Dual-action results: Plinest repairs DNA and stimulates collagen, while NCTF nourishes the skin with over 60 essential ingredients.
  • Minimally invasive with no downtime, thanks to a precision microcannula method invented at Clique Clinic.
  • Visible improvements in glow, hydration, and skin firmness can be seen within 2–4 weeks, with long-lasting cumulative effects.
  • Treats a wide range of skin concerns — from fine lines and dullness to post-acne scarring and loss of elasticity.
  • Exclusively developed and administered at Clique Clinic, Malaysia’s pioneer in regenerative aesthetics.

Introduction: The World’s First Regenerative Aesthetic Cocktail, Delivered with Precision via Microcannula

Regenerative aesthetics has redefined modern skincare by moving beyond surface-level solutions to therapies that stimulate true cellular rejuvenation.

At the forefront of this movement is the groundbreaking Pli-NCTF treatment, an advanced combination therapy designed to restore skin health from within. It incorporates the renowned NCTF 135HA ingredients, used widely in NCTF treatments across Malaysia and beyond.

Exclusively developed at Clique Clinic, this therapy merges scientific innovation with proven results to address aging, dullness, and damage at the root.

What Is Pli-NCTF Treatment?

Discover the game-changing Pli-NCTF therapy, a unique combination of polynucleotides (PN) and New Cellular Treatment Factor (NCTF) designed to rejuvenate, repair, and restore your skin at the cellular level. This innovative blend works synergistically to enhance skin quality, stimulate regeneration, and combat signs of aging from within.

Invented by Dr. Lim Ting Song, this revolutionary formula is piloted at Clique Clinic, Malaysia’s award-winning medical aesthetic center, known for its cutting-edge research and patient-centered treatments. The Pli-NCTF combination is not only backed by clinical data but is also a result of years of expertise and a deep understanding of the science behind skin regeneration.

Benefits of Combining Plinest + NCTF

The Pli-NCTF treatment is more than the sum of its parts. By combining Plinest — a polynucleotide-based skin healer with NCTF, a nutrient-rich mesotherapy cocktail, this dual-action protocol addresses both the underlying structure of the skin and its surface vitality.

Here’s how the combination unlocks superior results:

  1. Dual-Action Regeneration
    While Plinest works deep within the dermis to stimulate tissue repair and DNA regeneration, NCTF focuses on cellular nutrition and hydration. The result is a comprehensive approach that repairs, nourishes, and rejuvenates the skin from the inside out.
  1. Faster Visible Results
    Patients often notice a quicker glow and firmness because NCTF delivers immediate hydration and brightness, while Plinest continues to work at the cellular level over the following weeks. This fast-slow synergy ensures both immediate satisfaction and long-term improvement.
  1. Enhanced Skin Resilience
    By targeting both the skin’s structure (via polynucleotides) and its function (via micronutrients), this combination enhances the skin’s ability to resist environmental stress, inflammation, and aging — leading to longer-lasting resilience.
  1. Reduced Downtime, Increased Comfort
    Thanks to the microcannula technique and the biocompatibility of both solutions, the treatment is minimally invasive and suitable even for sensitive skin. Patients experience less irritation and a smoother recovery process.
  1. Broader Indication Coverage
    This combination therapy is highly versatile. It can be used to treat:
  • Fine lines and wrinkles
  • Loss of elasticity
  • Dehydrated or dull skin
  • Post-acne scarring
  • Redness and inflammation
  • Uneven skin tone and texture
  1. Ideal as a Standalone or Complementary Treatment
    Pli-NCTF can be used on its own or paired with other aesthetic treatments such as laser therapy, radiofrequency, or skin boosters, making it a flexible choice in personalized aesthetic plans.

Whether you’re looking to restore youthful radiance or repair stressed, aging skin, the Plinest + NCTF combination offers a comprehensive, evidence-based solution that activates your skin’s own healing intelligence.

The Science Behind the Innovation

Plinest is a polynucleotide-based bioregeneration treatment extracted from purified salmon DNA, which is bio-compatible with human tissue. These polynucleotides serve as building blocks for DNA and RNA synthesis, accelerating skin healing, reducing inflammation, and encouraging natural tissue regeneration.

NCTF (New Cellular Treatment Factor), developed by Fillmed Laboratories in France, is a powerful NCTF skin booster solution used in mesotherapy. It contains over 60 active ingredients, including vitamins, minerals, and antioxidants that restore youthful skin function.

The NCTF 135HA formulation replenishes the skin with essential nutrients that are diminished with age and environmental exposure.

Together, Plinest and NCTF injections enhance skin resilience, refine texture, and stimulate fibroblast activity — the cells responsible for collagen and elastin production.

5 Reasons Pli-NCTF is the Ultimate Anti-Aging Solution - NCTF 1

NCTF (New Cellular Treatment Factor), developed by Fillmed

  • 60 essential ingredients, at the perfect dosage
  • Provides an ideal environment for the cells
  • Improves cell bio-metabolism for all skin conditions
  • Efficiency & safety  proven by 45 years of experience
  • Award winning products from France with 13 vials injected EVERY MINUTE

Treatment Process: The Pli-NCTF® Protocol

This NCTF treatment is performed over 3 sessions across 2–8 weeks:

  1. Initialization Phase – Triggers initial skin activation

  2. Enhancing Phase – Builds on early improvements

  3. Boosting Phase – Maximizes long-term skin regeneration

Each session is minimally invasive and can be comfortably performed in our clinic with no downtime required.

5 Reasons Pli-NCTF is the Ultimate Anti-Aging Solution - PliNCTF protocol 3 sessions 2
PliNCTF Protocol

Key ingredients

Hyaluronic Acid – A powerful humectant that binds water to keep the skin hydrated and plump.

Amino Acids – The fundamental components for protein synthesis, aiding in skin repair and maintenance.

Antioxidants – Such as glutathione and vitamin C, which neutralize free radicals and reduce oxidative stress.

Vitamins (A, B, C, E) – Vital for promoting cellular turnover and improving skin radiance.

Minerals and Coenzymes – Support enzymatic reactions and improve overall skin function.

How Does Pli-NCTF Work?

  1. Collagen Stimulation – Polynucleotides support fibroblast proliferation, enhancing natural collagen and elastin synthesis.
  2. Deep Hydration – Hyaluronic acid and amino acids restore moisture levels deep within the dermis.
  3. Enhanced Cellular Repair – Accelerates the renewal of damaged skin cells, promoting a stronger and healthier epidermis.
  4. Antioxidant Protection – Defends against pollution, UV rays, and other stressors that accelerate skin aging.
  5. Restoration of Skin Barrier – Strengthens the skin’s natural defenses, preventing irritation and transepidermal water loss.
  6. Improved Microcirculation – Boosts blood flow to the skin, ensuring optimal delivery of oxygen and nutrients.
  7. Tissue Remodeling – Reduces the appearance of scars, enlarged pores, and pigmentation over time.

Microcannula method

This treatment protocol and its advanced microcannula delivery technique were invented by Dr. Lim Ting Song, a globally respected figure in regenerative aesthetics. With extensive experience in aesthetic medicine, Dr. Lim has developed this technique to ensure

  • Minimal discomfort
  • Greater safety
  • More even distribution of the product
  • Superior results with minimal downtime

The microcannula method offers the benefit of fewer entry points, reducing the risk of bruising and swelling. This allows for a more comfortable patient experience and enhances the even diffusion of the solution across larger treatment areas.

What to Expect

  • Quick 15–30 minute procedure – Perfect for a lunchtime rejuvenation session.
  • Minimal discomfort, bruising, and downtime – Return to your daily activities right after treatment.
  • Immediate skin improvements – Feel the hydration and glow instantly.
  • Progressive results over 2–4 weeks – The real magic happens as your skin begins to renew itself from within.
  • Long-lasting benefits – Sustained results with a cumulative effect after multiple sessions.
  • Safe for all skin types and tones – Dermatologically tested and clinically proven to be safe.
  • Customizable treatment plan – Can be tailored to target specific skin concerns or complement other aesthetic procedures.

Why Choose Clique Clinic?

  • Inventors of the Pli-NCTF protocol – Receive the treatment from the originators.
  • Global leaders in regenerative and anti-aging treatments – Recognized internationally for innovation.
  • Evidence-based, personalized approach – Treatments are designed around your individual skin profile.
  • State-of-the-art technology and internationally trained doctors – Delivering excellence in every session.
  • Dedicated patient care and education – Empowering you with knowledge and confidence every step of the way.

Who suitable in PliNCTF treatment?

  • Fine lines and wrinkles
  • Dull, dehydrated, or sagging skin
  • Post-acne scarring
  • Early signs of aging
  • Uneven tone and texture
  • Loss of skin elasticity
  • Sun damage and environmental stressors
  • Skin Redness

FAQ

It’s used to restore skin vitality, reduce fine lines, and improve texture through deep hydration and cellular nutrition.

While immediate glow is visible, optimal and long-lasting effects typically develop over 2–4 weeks post-treatment, with cumulative benefits over multiple sessions.

While traditional NCTF mesotherapy or microneedling injects NCTF into the skin using needles, the Pli-NCTF protocol at Clique Clinic uses a microcannula technique for greater safety, comfort, and even product distribution — without the downtime typically associated with microneedling.

NCTF is not a filler. Unlike dermal fillers that volumize, NCTF is a skin revitalization cocktail used in mesotherapy to improve skin quality and texture without altering facial volume.

Yes, NCTF 135HA is approved and available in Malaysia through authorised aesthetic clinics like Clique Clinic. It is used under medical supervision to ensure safety, quality, and effectiveness.

Yes, NCTF 135HA is available at Clique Clinic in Malaysia as part of the exclusive Pli-NCTF treatment protocol. Clique Clinic is the first to pioneer and offer this unique combination for regenerative skin therapy in the country.

Before treatment, a consultation is conducted to assess your skin. The actual procedure takes 15–30 minutes with minimal discomfort. After treatment, you may notice slight redness, which subsides quickly. Most patients resume normal activities the same day and begin to see results within days.

NCTF treatment is generally safe for all skin types. However, individuals with active infections, severe eczema, autoimmune disorders, or allergies to any components in the solution should consult a doctor for assessment.

Yes, when combined with regenerative therapies like Plinest, NCTF 135HA can help improve the appearance of acne scars, post-inflammatory pigmentation, and uneven skin texture by boosting collagen and cell renewal.

Pli-NCTF is unique to Clique Clinic Malaysia and combines the regenerative properties of Plinest with the revitalising effects of NCTF 135HA. Unlike typical skin boosters, this dual-approach works on both skin structure and nutrition for longer-lasting, deeper improvements.

Conclusion: Reclaim Your Radiance

Give your skin the ultimate regenerative boost with Pli-NCTF at Clique Clinic. Book your consultation today and experience the original Pli-NCTF cocktail — only where it was invented. Reveal a younger, healthier, and more luminous complexion with the power of science and innovation

This Post Has 2 Comments

  1. Suanne

    Enquiry about plinest + NCFT 135

    1. Kylie Wong

      Hi Suanne, our customer service representative has emailed you. Please check your mailbox or junk mail. Thank you

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