At Clique Clinic in Malaysia, our doctors often get asked about collagen, especially hydrolyzed collagen, and whether it truly makes a difference in skin health.

With the growing trend of collagen-based creams, serums, and supplements, it is important to separate marketing hype from real science. In this article, we explore where hydrolyzed collagen comes from, how it works, and what you can realistically expect when you include it in your skincare or wellness routine.

What is Hydrolyzed Collagen?

Hydrolyzed collagen, also known as collagen peptides, is collagen that has been broken down into smaller chains of amino acids through a process called hydrolysis. This makes it more water-soluble and easier for the body to absorb when ingested.

It can be derived from different sources, including:

• Marine sources such as fish skin and scales (hydrolyzed marine collagen, hydrolyzed fish collagen).
• Bovine sources, such as cow hides (hydrolyzed bovine collagen peptides).
• Porcine sources, such as pig skin.

In skincare, hydrolyzed collagen is primarily added as an ingredient to the overall formulation, and it is used for its ability to improve surface hydration by creating a smoother, more supple skin feel.

Chemical Composition & Properties of Hydrolyzed Collagen

Hydrolyzed collagen is rich in the amino acids glycine, proline, and hydroxyproline, which are the building blocks of natural collagen in our skin.

Compared to natural collagen molecules, once hydrolyzed, these peptides are much smaller in size, allowing them to dissolve easily in water and integrate well into topical formulations.

Its main properties include:

• Water solubility for easy incorporation into serums and creams.
• Film-forming ability to lock in moisture on the skin’s surface.
• Compatibility with other hydrating ingredients such as hyaluronic acid and glycerin.

Hydrolyzed Collagen vs Collagen Peptides

You may ask, “Which is better, collagen peptides or hydrolyzed collagen?”

The truth is, these terms refer to the same ingredient. Both are simply collagen broken down into smaller peptide chains.

What is Hydrolyzed Collagen Made From?

So, where does hydrolyzed collagen come from? Hydrolyzed collagen is sourced from:

• Marine collagen (fish skin and scales): For seafood collagen, the most popular one is hydrolyzed fish collagen, known for smaller peptide sizes, potentially better absorption, and sustainability when sourced responsibly.
• Bovine collagen (cow hide): Hydrolyzed bovine collagen peptides are a common and cost-effective source, rich in Type I and Type III collagen.
• Porcine collagen (pig skin): Structurally similar to human collagen but less commonly used in Malaysia due to cultural preferences.

If you are exploring hydrolyzed collagen powder or supplements, always check the source, especially if you have allergies or dietary restrictions.

What Type of Collagen is Hydrolyzed Collagen?

Most hydrolyzed collagen supplements contain Type I collagen, which is the most abundant collagen in skin, tendons, and bones.

Some blends also include Type III collagen, important for skin elasticity and firmness. Type II collagen is more associated with joint health rather than skin.

How Hydrolyzed Collagen Works in Skincare?

When applied topically, hydrolyzed collagen works mainly by forming a thin, invisible film over the skin’s surface, helping to reduce water loss. This gives the skin a plumper, more hydrated appearance. It does not penetrate deeply enough to replace lost collagen in the dermis, but it supports the skin barrier and smooths surface texture.

When taken orally, usually as hydrolyzed collagen supplements in the form of hydrolyzed collagen powder or hydrolyzed collagen pills, it is broken down in the digestive system into amino acids and peptides, which may help the body produce more collagen.

Hydrolyzed Collagen Benefits

Hydrolyzed collagen offers several benefits, especially when used consistently:

• Boosts skin hydration and elasticity: Topical application helps lock in moisture, while oral intake may enhance skin bounce over time.
• Reduces fine lines and roughness: The improved hydration makes fine lines less visible.
• Improves dry and dehydrated skin: Ideal for skin exposed to air-conditioning or Malaysia’s hot climate, where water loss can be high.
• Enhances smoothness and resilience: Skin feels softer, more supple, and less prone to tightness.

READ MORE: Results indicate that HC supplementation significantly improved skin elasticity

Hydrolyzed Collagen Side Effects & Considerations

• Generally safe for most skin types and dietary needs.
• Topical effects are limited to surface hydration; deeper collagen replenishment requires in-clinic treatments such as skin boosters, ultrasound like Ultheraphy, PDRN injections, or RF microneedling available at Clique Clinic.
• Those allergic to marine or animal-derived products should check the ingredient source before use.
• Pregnant or breastfeeding individuals should consult a healthcare provider before taking supplements.

For more on the safety and efficacy of collagen supplementation, see “Hydrolyzed Collagen, and concluded that it is safe for use in cosmetics”.

How to Use Hydrolyzed Collagen in Your Skincare Routine?

Hydrolyzed collagen is found in:

• Moisturizers for surface hydration.
• Serums for lightweight, water-based hydration.
• Sheet masks for a temporary plumping effect.
• Oral supplements, powders, and capsules for internal support.

Pairing hydrolyzed collagen with Vitamin C, peptides, and antioxidants can enhance the skin’s own collagen synthesis.

Best Way to Take Hydrolyzed Collagen

For supplements, research suggests a daily intake of 2.5 to 10 grams for visible skin benefits. Collagen powders can be mixed into water, coffee, or smoothies, while hydrolyzed collagen pills offer convenience. Results often require consistent use for at least 8 to 12 weeks.

READ MORE: Ingestion of hydrolyzed collagen for 90 days is effective in reducing skin aging

Who Should Use It?

Hydrolyzed collagen is suitable for:

• Individuals with dry, dehydrated, or aging skin.
• Individuals in their 30s and above who are experiencing reduced collagen production.
• Those seeking non-invasive ways to improve skin texture and hydration.

How Long Does Hydrolyzed Collagen Take to Work?

Skincare with hydrolyzed collagen can deliver immediate hydration, but these effects are temporary and fade within hours if not reapplied.

Oral collagen supplements require more patience; most studies show visible improvements in skin hydration and elasticity after 8 to 12 weeks of consistent intake.

As for which hydrolyzed collagen is best, the best choice depends on your dietary needs, budget, and sustainability preferences.

• Marine collagen has smaller peptides, so there is potentially better absorption.
• Bovine collagen is an affordable and effective solution for most skin needs.
• Blends of collagens may offer broader benefits.

This study supports the use of fish‐derived hydrolyzed collagen for the improvement of skin health in an aging population.

Final Thoughts

Hydrolyzed collagen is a versatile ingredient that can support your skin’s hydration and smoothness. While topical forms act mainly on the surface, hydrolyzed collagen supplements may provide deeper benefits over time when combined with a balanced diet and sun protection.

At Clique Clinic, our doctors often recommend a multi-pronged approach to skin health, which is combining daily skincare with clinically proven treatments such as skin boosters, ultrasound like Ultheraphy, PDRN therapy, or RF microneedling for more significant collagen stimulation.

If you are considering adding hydrolyzed collagen to your routine, our team can guide you on the right products and treatments tailored to your skin needs.

To find out more about how we can help you achieve healthier, firmer skin, contact Clique Clinic for a personalised consultation @wa.me/60123537960.